FDA Sentinel Initiative

FDA's active safety-surveillance initiative using distributed electronic healthcare data to evaluate the safety of regulated medical products.

Resource family Pharmacoepidemiology & Rwe
Resource type Active Safety Surveillance And Distributed Data Network
Maintained by US Food and Drug Administration
Jurisdiction United States
Status Official FDA active safety-surveillance programme
Access Public programme information; analytical network access is governed
Official link verified 2026-09-04
Official source Visit official resource ↗

FDA Sentinel supports active post-market safety surveillance using electronic healthcare data in a distributed analytical network. It is a key reference for understanding how FDA complements spontaneous reporting with real-world evidence methods.