Good Pharmacovigilance Practices (GVP)

EMA's official collection of EU Good Pharmacovigilance Practices modules and product- or population-specific considerations.

Resource family Legislation & Regulatory Guidance
Resource type Regulatory Guidance
Maintained by European Medicines Agency
Jurisdiction European Union / EEA
Status EU regulatory guidance
Access Public
Official link verified 2026-09-04
Official source Visit official resource ↗

Good Pharmacovigilance Practices (GVP) provide the principal EU regulatory guidance for performing pharmacovigilance activities under the EU legislative framework.

Why a pharmacovigilance professional uses it

The GVP modules explain how the EU pharmacovigilance framework is implemented across areas including pharmacovigilance systems and quality systems, the PSMF, inspections, audits, risk management, ICSR management, PSURs, PASS, signal management, additional monitoring, safety communication and risk-minimisation measures.

Regulatory status

GVP is guidance. It should be interpreted together with applicable EU legislation, including Directive 2001/83/EC, Regulation (EC) No 726/2004 and relevant implementing measures. QPPV.com distinguishes the legal requirement from the GVP explanation of how that requirement is operationalised.