IME List — Important Medical Events

EMA reference list supporting suspected adverse-reaction classification, case assessment and aggregated safety-data analysis.

Resource family Signals & Safety Communications
Resource type Medical Event Reference List
Maintained by European Medicines Agency
Jurisdiction European Union
Status Regulatory reference resource
Access Public
Official link verified 2026-10-17
Official source Visit official resource ↗

The Important Medical Events (IME) list supports classification of suspected adverse reactions, case assessment and aggregated data analysis. It is guidance and does not replace medical judgement in assessing seriousness.

Use the Important medical event list section of the official EMA page for the current list and inclusion/exclusion criteria. EMA maintains the list in line with MedDRA releases.

Read the QPPV guide to the IME list.

QPPV.com