EMA PSUR Repository

EU repository used by marketing-authorisation holders to submit periodic safety update reports for human medicines.

Resource family Aggregate Reporting Resources
Resource type Regulatory Submission Repository
Maintained by European Medicines Agency
Jurisdiction European Union / EEA
Status Official EU PSUR submission infrastructure
Access Restricted submission access; public guidance
Official link verified 2026-09-04
Official source Visit official resource ↗

The PSUR Repository is the central EU infrastructure for periodic safety update report submissions for human medicines.

Core official resources

Practical use

For EU human medicines, the repository is the operational destination for PSUR submissions rather than separate submission to individual national competent authorities. Users should distinguish the repository itself from the EURD list, which determines whether and when many active substances require PSUR submission and whether the assessment follows a PSUSA procedure.